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| Nomenclature |
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Symbol:
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Slc4a7tm1Krtz
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Name:
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solute carrier family 4, sodium bicarbonate cotransporter, member 7;
targeted mutation 1, Ira Kurtz
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MGI ID: |
MGI:2682641 |
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Synonyms: |
Slc4a7- |
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Gene:
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Slc4a7
Location:
Chr14:14703025-14799943 bp, + strand
Genetic Position: Chr14,
7.08 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:86635
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Parent Cell Line:
| Lex-1 (ES Cell) |
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Strain of Origin:
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129S5/SvEvBrd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A 3' portion of exon 5 was replaced with a MC1-neo cassette. Protein was undetected by Western blot analysis of homozygous mutant mice using a C-terminal antibody. (J:86635)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Slc4a7 Mutation:
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10 strains or lines available |
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| References |
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Original: |
J:86635
Bok D et al.,
"Blindness and auditory impairment caused by loss of the sodium bicarbonate cotransporter NBC3."
Nat Genet 2003 Jul;34(3):313-9
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All: |
3 reference(s)
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Analysis Tools
