|
|
| Nomenclature |
|
Symbol:
|
Krt2Dsk2
|
|
Name:
|
keratin 2;
dark skin 2
|
|
MGI ID: |
MGI:2682236 |
|
Gene:
|
Krt2
Location:
Chr15:101810689-101818169 bp, - strand
Genetic Position: Chr15,
57.03 cM
|
|
Mutation
origin |
|
Strain of Origin:
|
C3HeB/J
|
|
Mutation
description |
|
Allele
Type: | |
Chemically induced (ENU) |
|
Mutation: | |
Single point mutation |
| |
|
Mutation details: The mutation was identified as an A to C transversion causing a missense mutation that predicts a Thr5000Pro substitution in the rod 2b domain, a domain known to be important for keratin keratin interactions. (J:81301)
|
|
Inheritance: | |
Dominant |
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Krt2 Mutation:
|
2 strains or lines available |
|
| References |
|
Original: |
J:81301
Fitch KR et al.,
"Genetics of dark skin in mice."
Genes Dev 2003 Jan 15;17(2):214-28
|
|
All: |
1 reference(s)
|
|
Analysis Tools
