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| Nomenclature |
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Symbol:
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Nbntm1Zqw
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Name:
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nibrin;
targeted mutation 1, Zhao-Qi Wang
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MGI ID: |
MGI:2682000 |
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Synonyms: |
Nbn-, Nbnins-6 |
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Gene:
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Nbn
Location:
Chr4:15957925-15992589 bp, + strand
Genetic Position: Chr4,
6.66 cM, cytoband A
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:86563
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Exon 6 was disrupted by the insertion of a neomycin selection cassette. (J:86563)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Nbn Mutation:
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14 strains or lines available |
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| References |
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Original: |
J:86563
Dumon-Jones V et al.,
"Nbn heterozygosity renders mice susceptible to tumor formation and ionizing radiation-induced tumorigenesis."
Cancer Res 2003 Nov 1;63(21):7263-9
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All: |
4 reference(s)
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Analysis Tools
