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| Nomenclature |
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Symbol:
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Fbln5tm1Krc
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Name:
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fibulin 5;
targeted mutation 1, Kenneth R Chien
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MGI ID: |
MGI:2681527 |
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Synonyms: |
fibulin-5- |
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Gene:
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Fbln5
Location:
Chr12:101746565-101819055 bp, - strand
Genetic Position: Chr12,
51.29 cM, cytoband F1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:86753
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The insertion of a cassette containing lacZ and neo replaced the first 4 exons of the endogenous gene. Transcript was undetected in homozygous mutant mice by Northern blot analysis and in situ hybridization of the pulmonary artery and lungs. (J:86753)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Fbln5 Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:86753
Nakamura T et al.,
"Fibulin-5/DANCE is essential for elastogenesis in vivo."
Nature 2002 Jan 10;415(6868):171-5
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All: |
2 reference(s)
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Analysis Tools
