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| Nomenclature |
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Symbol:
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Artm1Ska
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Name:
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androgen receptor;
targeted mutation 1, Shigeaki Kato
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MGI ID: |
MGI:2681507 |
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Synonyms: |
ARKO |
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Gene:
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Ar
Location:
ChrX:98149721-98323215 bp, + strand
Genetic Position: ChrX,
42.82 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:85484
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Parent Cell Line:
| TT2 (ES Cell) |
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Strain of Origin:
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(C57BL/6NCrlj x CBA/JNCrlj)F1
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A loxP site was inserted upstream of exon 1 and a floxed neomycin resistance cassette was introduced downstream. Cre mediated excision results in disruption of the gene. No mRNA transcripts were detected in the brain by Northern blot analysis and RT-PCR. Protein product was undetectable immunologically. This allele was generated from Artm2Ska. (J:85484, J:88153)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:85484
Matsumoto T et al.,
"Androgen receptor functions from reverse genetic models."
J Steroid Biochem Mol Biol 2003 Jun;85(2-5):95-9
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All: |
12 reference(s)
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Analysis Tools
