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| Nomenclature |
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Symbol:
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Gabrg2tm2Lusc
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Name:
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gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2;
targeted mutation 2, Bernhard Luscher
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MGI ID: |
MGI:2680624 |
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Synonyms: |
fgamma2 |
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Gene:
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Gabrg2
Location:
Chr11:41910203-42000857 bp, - strand
Genetic Position: Chr11,
24.8 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:86221
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Exon 8 was left flanked by single loxP sites after an frt flanked neo cassette was excised via Flp-mediated recombination. A single flp site was left immediately downstream of the 3' loxP site. (J:86221)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:86221
Schweizer C et al.,
"The gamma2 subunit of GABA(A) receptors is required for maintenance of receptors at mature synapses."
Mol Cell Neurosci 2003 Oct;24(2):442-50
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All: |
3 reference(s)
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Analysis Tools
