|
|
| Nomenclature |
|
Symbol:
|
Tg(Tcra/Tcrb)1Vbo
|
|
Name:
|
transgene insertion 1, Harald von Boehmer
|
|
MGI ID: |
MGI:2680176 |
|
Synonyms: |
6.5 TcR, HA TCR, SFE TCR, TCR-HA, TCR-SFE, TS1 |
|
Transgene:
|
Tg(Tcra/Tcrb)1Vbo
Location:
unknown
|
|
Transgene origin |
|
Strain of Origin:
|
(C57BL/6J x DBA/2J)F2
|
|
Transgene description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The transgenic construct expresses a T cell receptor specific for peptide 111-119 from influenza hemagglutinin (HA), presented by class II I-Ed MHC molecules. The receptor is encoded by Tcrb-V8.2, Tcrb-J, Tcra-V4, and Tcra-J. (J:86429)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
| References |
|
Original: |
J:86429
Kirberg J et al.,
"Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor."
J Exp Med 1994 Jul 1;180(1):25-34
|
|
All: |
67 reference(s)
|
|