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| Nomenclature |
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Symbol:
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Id3tm1Zhu
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Name:
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inhibitor of DNA binding 3;
targeted mutation 1, Yuan Zhuang
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MGI ID: |
MGI:2679967 |
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Synonyms: |
Id3- |
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Gene:
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Id3
Location:
Chr4:136143497-136145755 bp, + strand
Genetic Position: Chr4,
68.34 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:56950
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Parent Cell Line:
| AK7 (ES Cell) |
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Strain of Origin:
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129S4/SvJaeSor
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The first 2 exons and part of exon 3 were replaced by a PGK neomycin cassette. Gene disruption was confirmed by Northern blot analysis. (J:56950)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:56950
Pan L et al.,
"Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene."
Mol Cell Biol 1999 Sep;19(9):5969-80
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All: |
39 reference(s)
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Analysis Tools
