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| Nomenclature |
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Symbol:
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Cplx2tm1Rmnd
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Name:
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complexin 2;
targeted mutation 1, Christian Rosenmund
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MGI ID: |
MGI:2679626 |
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Synonyms: |
CPX II- |
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Gene:
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Cplx2
Location:
Chr13:54371349-54383917 bp, + strand
Genetic Position: Chr13,
28.59 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:86365
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: All three coding exons were replaced by a neomycin cassette. Western blot analysis of adult brains demonstrated the abolition of protein product expression. (J:86365)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cplx2 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:86365
Reim K et al.,
"Complexins regulate a late step in Ca2+-dependent neurotransmitter release."
Cell 2001 Jan 12;104(1):71-81
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All: |
11 reference(s)
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Analysis Tools
