Tg(MMTV-PyVT)634Mul
Transgene Detail
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| Nomenclature |
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Symbol:
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Tg(MMTV-PyVT)634Mul
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Name:
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transgene insertion 634, William Muller
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MGI ID: |
MGI:2679595 |
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Synonyms: |
MMTV-PyMT, MMTV-PyVmT, MTAG, PyMT, PyV-mT, PyVT, Tg(MMTVPyVT)634Mul, TgN(MMTVPyVT)634Mul |
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Transgene:
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Tg(MMTV-PyVT)634Mul
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene expresses polyoma virus middle T antigen under the control of the mouse mammary tumor virus LTR. Expression of this transgene was detected at high levels in male and female mammary glands. Other expression sites include salivary gland, seminal vesicles, ovaries, and lung. (J:46460)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Additional lines produced include lines 121, 196, 235, 654, 668, 670.
These mice are used to study metastatic disease.
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| References |
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Original: |
J:46460
Guy CT et al.,
"Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease."
Mol Cell Biol 1992 Mar;12(3):954-61
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All: |
186 reference(s)
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Analysis Tools
