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| Nomenclature |
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Symbol:
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Fastm1Vbo
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Name:
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Fas (TNF receptor superfamily member 6);
targeted mutation 1, Harald von Boehmer
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MGI ID: |
MGI:2679555 |
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Synonyms: |
fasfl |
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Gene:
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Fas
Location:
Chr19:34290659-34327770 bp, + strand
Genetic Position: Chr19,
29.48 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:85985
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
| |
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Exon 9, the death domain encoding exon, was flanked by single loxP sites. (J:85985)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Fas Mutation:
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35 strains or lines available |
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| References |
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Original: |
J:85985
Apostolou I et al.,
"Effective destruction of Fas-deficient insulin-producing beta cells in type 1 diabetes."
J Exp Med 2003 Oct 6;198(7):1103-6
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All: |
4 reference(s)
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Analysis Tools
