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| Nomenclature |
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Symbol:
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Smad5tm1Huy
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Name:
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SMAD family member 5;
targeted mutation 1, Danny Huylebroeck
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MGI ID: |
MGI:2679441 |
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Synonyms: |
Smad5flE2, Smad5flox, Smad5fx, Smad5fx(exon2) |
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Gene:
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Smad5
Location:
Chr13:56703010-56742377 bp, + strand
Genetic Position: Chr13,
30.12 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:86157
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Exon 2 was flanked by single loxP sites. Exon 2 contains the translational start codon and approximately one-third of the protein coding sequence. (J:86157)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Smad5 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:86157
Umans L et al.,
"Generation of a floxed allele of Smad5 for cre-mediated conditional knockout in the mouse."
Genesis 2003 Sep;37(1):5-11
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All: |
16 reference(s)
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Analysis Tools
