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| Nomenclature |
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Symbol:
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Arnttm1.2Gonz
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Name:
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aryl hydrocarbon receptor nuclear translocator;
targeted mutation 1.2, Frank Gonzalez
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MGI ID: |
MGI:2679362 |
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Synonyms: |
Arntdelta |
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Gene:
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Arnt
Location:
Chr3:95434388-95497237 bp, + strand
Genetic Position: Chr3,
40.74 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:85934
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Parent Cell Line:
| RW-4 (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A single loxP site remained in place of exon 6 after the floxed region encompassing a neo cassette and exon 6 was excised from Arnttm1Gonz via cre mediated recombination in the germline. (J:85934)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Arnt Mutation:
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17 strains or lines available |
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| References |
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Original: |
J:85934
Tomita S et al.,
"T cell-specific disruption of arylhydrocarbon receptor nuclear translocator (Arnt) gene causes resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced thymic involution."
J Immunol 2003 Oct 15;171(8):4113-20
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All: |
2 reference(s)
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