Tg(ACTB-cre)1Tes
Transgene Detail
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| Nomenclature |
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Symbol:
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Tg(ACTB-cre)1Tes
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Name:
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transgene insertion 1, Lino Tessarollo
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MGI ID: |
MGI:2677702 |
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Transgene:
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Tg(ACTB-cre)1Tes
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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Not Specified
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: The sequence encoding cre recombinase was under the control of the human beta-actin promoter. This line differs from other beta-actin driven transgenes in that expression was driven during early embryogenesis in a stochastic manner. While uniform transgenic expression was detected in the testis, mosaic patterns of cre-mediated recombination were observed in various organs including the liver, heart, lung, pancreas, brain, retina, spleen, and adrenal gland. (J:85513)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:85513
Ma W et al.,
"Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene."
Cancer Res 2003 Sep 1;63(17):5320-8
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All: |
4 reference(s)
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Analysis Tools
