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| Nomenclature |
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Symbol:
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Vhltm1.1Lss
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Name:
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von Hippel-Lindau tumor suppressor;
targeted mutation 1.1, Laura S Schmidt
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MGI ID: |
MGI:2677579 |
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Synonyms: |
VHLd |
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Gene:
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Vhl
Location:
Chr6:113623959-113631633 bp, + strand
Genetic Position: Chr6,
52.81 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:85513
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The floxed region containing exons 2 and 3 was excised from Vhltm1Lss via cre-mediated recombination. (J:85513)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Vhl Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:85513
Ma W et al.,
"Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene."
Cancer Res 2003 Sep 1;63(17):5320-8
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All: |
4 reference(s)
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Analysis Tools
