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| Nomenclature |
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Symbol:
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Hba-xtm1Led
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Name:
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hemoglobin X, alpha-like embryonic chain in Hba complex;
targeted mutation 1, Philip Leder
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MGI ID: |
MGI:2677497 |
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Synonyms: |
zeta-, zeta-null |
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Gene:
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Hba-x
Location:
Chr11:32276400-32278116 bp, + strand
Genetic Position: Chr11,
18.86 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:41934
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Parent Cell Line:
| TC1/TC-1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: A neomycin selection cassette was inserted into the first exon of the gene. Northern blot analysis on RNA derived from homozygous embryos demonstrated that no detectable transcript is expressed from this allele. (J:41934)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:41934
Leder A et al.,
"Mouse zeta- and alpha-globin genes: Embryonic survival, alpha-thalassemia, and genetic background effects."
Blood 1997 AUG 1;90(3):1275-1282
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All: |
2 reference(s)
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Analysis Tools
