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| Nomenclature |
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Symbol:
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Stk11tm1.1Jish
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Name:
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serine/threonine kinase 11;
targeted mutation 1.1, Kou-ichi Jishage
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MGI ID: |
MGI:2676546 |
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Synonyms: |
Lkb1- |
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Gene:
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Stk11
Location:
Chr10:80115803-80130682 bp, + strand
Genetic Position: Chr10,
39.72 cM
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Growth retardation, impaired embryo turning and small somites in Stk11tm1.1Jish/Stk11tm1.1Jish embryos
Show the 2 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:77213
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Parent Cell Line:
| AB2.2 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprtb-m2
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The floxed sequence of Stk11tm1Jish, encompassing exons 2 through 8, was excised via cre-mediated recombination in the germline. (J:77213)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Stk11 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:77213
Jishage K et al.,
"Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis."
Proc Natl Acad Sci U S A 2002 Jun 25;99(13):8903-8
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All: |
1 reference(s)
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Analysis Tools
