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| Nomenclature |
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Symbol:
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Ctf1tm1Msd
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Name:
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cardiotrophin 1;
targeted mutation 1, Michael Sendtner
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MGI ID: |
MGI:2675769 |
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Synonyms: |
ct-1 - |
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Gene:
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Ctf1
Location:
Chr7:127712736-127718185 bp, + strand
Genetic Position: Chr7,
69.69 cM, cytoband F3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:77294
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin selection cassette replaced a genomic fragment spanning exon 2 and the complete coding region of exon 3. In situ hybridization studies on homozygous embryos demonstrated that no detectable transcript is expressed from this allele. (J:77294)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ctf1 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:77294
Oppenheim RW et al.,
"Cardiotrophin-1, a muscle-derived cytokine, is required for the survival of subpopulations of developing motoneurons."
J Neurosci 2001 Feb 15;21(4):1283-91
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All: |
8 reference(s)
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Analysis Tools
