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| Nomenclature |
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Symbol:
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Ptch1tm1Bjw
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Name:
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patched homolog 1;
targeted mutation 1, Brandon J Wainwright
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MGI ID: |
MGI:2675356 |
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Synonyms: |
Ptc1lox, Ptch1c, Ptch1flox, Ptch1neo |
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Gene:
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Ptch1
Location:
Chr13:63511533-63565520 bp, - strand
Genetic Position: Chr13,
32.8 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:85040
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Parent Cell Line:
| C1368 (ES Cell) |
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Strain of Origin:
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129T2/SvEms
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Exon 3 was flanked by a single upstream loxP site in intron 2 and an FRT-neo-FRT-loxP cassette in intron 3. Mice carrying this allele were used to generate Ptchtm1.1Bjw. (J:85040)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ptch1 Mutation:
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22 strains or lines available |
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| References |
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Original: |
J:85040
Ellis T et al.,
"Patched 1 conditional null allele in mice."
Genesis 2003 Jul;36(3):158-61
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All: |
24 reference(s)
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