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| Nomenclature |
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Symbol:
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Tg(Hoxb7-cre)13Amc
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Name:
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transgene insertion 13, Andrew P McMahon
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MGI ID: |
MGI:2675121 |
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Synonyms: |
Hoxb7-Cre, HoxB7Cre, HoxB7/Cre |
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Transgene:
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Tg(Hoxb7-cre)13Amc
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: A transgenic construct containing the 1.3Kb enhancer and promoter sequence upstream of the of mouse homeo box B7 gene, a human growth factor mini gene and the Cre coding sequence was injected into fertilized C57BL/6 mouse eggs. Cre recombinase expression is detected in the mesonephric duct as early as embryonic day 9.5, in the ureteric bud by embryonic day 10.25 and in all ureteric bud epithelial cells by embryonic day 12.5. Low levels of expression are detected in the dorsal root ganglia and the spinal cord. (J:79481, J:100575)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:79481
Yu J et al.,
"Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney."
Development 2002 Nov;129(22):5301-12
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All: |
41 reference(s)
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Analysis Tools
