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| Nomenclature |
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Symbol:
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Cacna1ctm3Hfm
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Name:
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calcium channel, voltage-dependent, L type, alpha 1C subunit;
targeted mutation 3, Franz Hofmann
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MGI ID: |
MGI:2674119 |
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Synonyms: |
Cav1.2L2, L2 |
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Gene:
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Cacna1c
Location:
Chr6:118592319-118780324 bp, - strand
Genetic Position: Chr6,
55.86 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:66242
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Exons 14 and 15 were left flanked by single loxP sites. This allele was generated using ES cells that were also used to generate Cacna1ctm2Hfm. (J:66242)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cacna1c Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:66242
Seisenberger C et al.,
"Functional embryonic cardiomyocytes after disruption of the L-type alpha 1C (Cav1.2) calcium channel gene in the mouse"
J Biol Chem 2000 Dec 15;275(50):39193-9
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All: |
16 reference(s)
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Analysis Tools
