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| Nomenclature |
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Symbol:
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Tg(HD82Gln)81Dbo
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Name:
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transgene insertion 81, David R Borchelt
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MGI ID: |
MGI:2670626 |
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Synonyms: |
HD-N171-82Q, N171-82Q, TGN(HD82Gln)81Dbo |
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Transgene:
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Tg(HD82Gln)81Dbo
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgenic line expresses an N-terminally truncated human huntingtin cDNA that encodes 82 glutamines and encompasses the first 171 amino acids. The altered huntingtin cDNA is under control of a mouse prion protein promoter, which drives transgene expression in the neurons of the central nervous system (J:53797)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:53797
Schilling G et al.,
"Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin [published erratum appears in Hum Mol Genet 1999 May;8(5):943]"
Hum Mol Genet 1999 Mar;8(3):397-407
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All: |
40 reference(s)
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Analysis Tools
