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| Nomenclature |
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Symbol:
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Gnpattm1Just
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Name:
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glyceronephosphate O-acyltransferase;
targeted mutation 1, Wilhelm W Just
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MGI ID: |
MGI:2670461 |
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Synonyms: |
DAPAT- |
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Gene:
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Gnpat
Location:
Chr8:124863033-124890057 bp, + strand
Genetic Position: Chr8,
72.81 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:84690
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 5 through 7 were replaced by a neomycin selection cassette. Protein was undetected by Western blot analysis of protein extracts obtained from the Harderian glands of homozygous mutant mice. (J:84690)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gnpat Mutation:
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10 strains or lines available |
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| References |
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Original: |
J:84690
Rodemer C et al.,
"Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice."
Hum Mol Genet 2003 Aug 1;12(15):1881-95
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All: |
5 reference(s)
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Analysis Tools
