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| Nomenclature |
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Symbol:
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Neurod6tm1(cre)Kan
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Name:
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neurogenic differentiation 6;
targeted mutation 1, Klaus-Armin Nave
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MGI ID: |
MGI:2668659 |
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Synonyms: |
Math2/Cre, Neurod6/Cre, NexCre, NEX-Cre |
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Gene:
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Neurod6
Location:
Chr6:55677818-55681263 bp, - strand
Genetic Position: Chr6,
27.53 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:62118
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: The endogenous locus was disrupted by the insertion of a cassette containing cre recombinase followed by a neomycin resistance gene in exon 2. The endogenous promoter drove expression of cre in the granule cells of the hippocampus. (J:62118, J:117061)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Neurod6 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:62118
Schwab MH et al.,
"Neuronal basic helix-loop-helix proteins (NEX and BETA2/Neuro D) regulate terminal granule cell differentiation in the hippocampus."
J Neurosci 2000 May 15;20(10):3714-24
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All: |
69 reference(s)
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Analysis Tools
