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| Nomenclature |
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Symbol:
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Prkg1tm2Naw
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Name:
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protein kinase, cGMP-dependent, type I;
targeted mutation 2, Hermann Nawrath
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MGI ID: |
MGI:2668652 |
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Synonyms: |
CGKIL2 |
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Gene:
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Prkg1
Location:
Chr19:30569238-31764822 bp, - strand
Genetic Position: Chr19,
25.17 cM, cytoband C2
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:84611
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Exon 10 was left flanked by loxP sites after the homologous recombination of a targeting vector containing a single loxP site upstream of exon 10 and tk-neo cassette with a 3' loxP site in intron 10. (J:84611)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Prkg1 Mutation:
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12 strains or lines available |
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| References |
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Original: |
J:84611
Wegener JW et al.,
"cGMP-dependent protein kinase I mediates the negative inotropic effect of cGMP in the murine myocardium."
Circ Res 2002 Jan 11;90(1):18-20
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All: |
9 reference(s)
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Analysis Tools
