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| Nomenclature |
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Symbol:
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Serpini1tm1Dpw
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Name:
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serine (or cysteine) peptidase inhibitor, clade I, member 1;
targeted mutation 1, David Paul Wolfer
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MGI ID: |
MGI:2668495 |
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Synonyms: |
Ns - |
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Gene:
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Serpini1
Location:
Chr3:75557547-75643495 bp, + strand
Genetic Position: Chr3,
33.76 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:84427
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Parent Cell Line:
| GS1 (ES Cell) |
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Strain of Origin:
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129/Sv
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: A neo cassette was inserted into exon 2. Western blot analysis demonstrated the absence of gene product in homozygotes. (J:84427)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:84427
Madani R et al.,
"Impaired explorative behavior and neophobia in genetically modified mice lacking or overexpressing the extracellular serine protease inhibitor neuroserpin."
Mol Cell Neurosci 2003 Jul;23(3):473-94
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All: |
2 reference(s)
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Analysis Tools
