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| Nomenclature |
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Symbol:
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Mgat2tm1.1Jxm
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Name:
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mannoside acetylglucosaminyltransferase 2;
targeted mutation 1.1, Jamey Marth
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MGI ID: |
MGI:2667740 |
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Synonyms: |
Mgat2delta |
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Gene:
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Mgat2
Location:
Chr12:69184157-69186770 bp, + strand
Genetic Position: Chr12,
28.73 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:80661
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The entire coding region, which is contained within a single exon, was deleted when the flanking loxP sites present in Mgat2tm1Jxm were recombined in the germline. (J:80661)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Mgat2 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:80661
Wang Y et al.,
"Modeling human congenital disorder of glycosylation type IIa in the mouse: conservation of asparagine-linked glycan-dependent functions in mammalian physiology and insights into disease pathogenesis."
Glycobiology 2001 Dec;11(12):1051-70
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All: |
2 reference(s)
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Analysis Tools
