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| Nomenclature |
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Symbol:
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Nsd1tm1.1Pcn
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Name:
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nuclear receptor-binding SET-domain protein 1;
targeted mutation 1.1, Pierre Chambon
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MGI ID: |
MGI:2667262 |
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Synonyms: |
NSD1- |
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Gene:
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Nsd1
Location:
Chr13:55209782-55318325 bp, + strand
Genetic Position: Chr13,
29.8 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:83923
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Parent Cell Line:
| P1 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: This allele was generated by crossing mice heterozygous for Nsd1tm1Pcn with cytomegalovirus-Cre mice which express the Cre recombinase in the germline. Animals in which Cre-mediated excision of the neomycin gene and exon 2 occurred were detected by PCR analysis. (J:83923)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:83923
Rayasam GV et al.,
"NSD1 is essential for early post-implantation development and has a catalytically active SET domain."
EMBO J 2003 Jun 16;22(12):3153-63
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All: |
1 reference(s)
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Analysis Tools
