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| Nomenclature |
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Symbol:
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Pde6brd1-2J
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Name:
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phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide;
retinal degeneration 1, 2 Jackson
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MGI ID: |
MGI:2665102 |
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Synonyms: |
neuroscience mutagenesis facility, 137, nmf137, NMF137, Pde6b2J, Pde6bnmf137 |
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Gene:
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Pde6b
Location:
Chr5:108388391-108432397 bp, + strand
Genetic Position: Chr5,
53.07 cM
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Nucleotide substitutions |
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Mutation details: This mutation was shown by genetic complementation analysis to be an allele of Pde6b. Molecular sequence analysis showed that this mutation corresponds to a point mutation in exon 16.
(J:122722)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:122722
Chang B et al.,
"Two mouse retinal degenerations caused by missense mutations in the beta-subunit of rod cGMP phosphodiesterase gene."
Vision Res 2007 Mar;47(5):624-33
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All: |
3 reference(s)
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Analysis Tools
