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| Nomenclature |
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Symbol:
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Tnfrsf9tm1Byk
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Name:
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tumor necrosis factor receptor superfamily, member 9;
targeted mutation 1, Byoung Kwon
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MGI ID: |
MGI:2664914 |
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Synonyms: |
4-1BB-, 4-1BB-KO, CD137- |
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Gene:
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Tnfrsf9
Location:
Chr4:150914562-150946102 bp, + strand
Genetic Position: Chr4,
81.52 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:83996
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Parent Cell Line:
| Other (see notes) (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: The gene was disrupted by insertion of a neomycin resistance cassette into the translation initiation site. (J:83996)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Authors give the ES cell line as E13TG2a.
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| References |
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Original: |
J:83996
Kwon BS et al.,
"Immune responses in 4-1BB (CD137)-deficient mice."
J Immunol 2002 Jun 1;168(11):5483-90
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All: |
42 reference(s)
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Analysis Tools
