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| Nomenclature |
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Symbol:
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Hbbtm1Tow
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Name:
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hemoglobin beta chain complex;
targeted mutation 1, Timothy Townes
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MGI ID: |
MGI:2664239 |
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Synonyms: |
Hbb0, Hbbtm1Tmt |
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Gene:
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Hbb
Location:
unknown
Genetic Position: Chr7,
Syntenic
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:29087
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
| |
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Mutation details: A genomic fragment encompassing all of Hbb-b1 and a 5' portion of Hbb-b2 was replaced with a neo cassette inserted by homologous recombination. (J:29087)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:29087
Ciavatta DJ et al.,
"Mouse model of human beta zero thalassemia: targeted deletion of the mouse beta maj- and beta min-globin genes in embryonic stem cells."
Proc Natl Acad Sci U S A 1995 Sep 26;92(20):9259-63
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All: |
45 reference(s)
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Analysis Tools
