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| Nomenclature |
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Symbol:
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Slit3tm1.1Dor
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Name:
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slit homolog 3 (Drosophila);
targeted mutation 1.1, David M Ornitz
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MGI ID: |
MGI:2662358 |
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Gene:
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Slit3
Location:
Chr11:35121224-35708507 bp, + strand
Genetic Position: Chr11,
20.29 cM, cytoband A5
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:83292
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The floxed neo cassette was excised from Slit3tm1Dor via cre-mediated recombination. The Beta-gal gene was left in place of the the 3' portion of exon 1 (194 nt) and approximately 800 nt of intron 1. (J:83292)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:83292
Yuan W et al.,
"A genetic model for a central (septum transversum) congenital diaphragmatic hernia in mice lacking Slit3."
Proc Natl Acad Sci U S A 2003 Apr 29;100(9):5217-22
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All: |
12 reference(s)
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Analysis Tools
