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| Nomenclature |
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Symbol:
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Ppp1r3ctm1Ars
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Name:
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protein phosphatase 1, regulatory (inhibitor) subunit 3C;
targeted mutation 1, Alan R Saltiel
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MGI ID: |
MGI:2662307 |
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Synonyms: |
PTG- |
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Gene:
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Ppp1r3c
Location:
Chr19:36731731-36736604 bp, - strand
Genetic Position: Chr19,
31.89 cM, cytoband C3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:83297
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129/Sv
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Disruption caused by insertion of vector |
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Mutation details: The entire coding region was replaced with a neo cassette inserted by homologous recombination. Western blot analysis of adipose, liver, and muscle tissue showed reduced levels of protein in homozygous mutant mice. (J:83297)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ppp1r3c Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:83297
Crosson SM et al.,
"PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance."
J Clin Invest 2003 May;111(9):1423-32
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All: |
1 reference(s)
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Analysis Tools
