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| Nomenclature |
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Symbol:
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Arg1tm1Rki
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Name:
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arginase, liver;
targeted mutation 1, Ramaswamy K Iyer
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MGI ID: |
MGI:2660809 |
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Synonyms: |
AI - |
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Gene:
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Arg1
Location:
Chr10:24915208-24927470 bp, - strand
Genetic Position: Chr10,
12.26 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:83263
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin selection cassette replaced a genomic fragment containing exon 4. Activity assays demonstrated that no functional protein was made from this allele. (J:83263)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:83263
Iyer RK et al.,
"Mouse model for human arginase deficiency."
Mol Cell Biol 2002 Jul;22(13):4491-8
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All: |
10 reference(s)
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Analysis Tools
