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| Nomenclature |
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Symbol:
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Mocs1tm1Jre
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Name:
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molybdenum cofactor synthesis 1;
targeted mutation 1, Jochen Reiss
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MGI ID: |
MGI:2659140 |
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Synonyms: |
MOCS1 - |
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Gene:
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Mocs1
Location:
Chr17:49428362-49455435 bp, + strand
Genetic Position: Chr17,
25.45 cM, cytoband C
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:80807
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin selection cassette replaced exon 3 and flanking sequences. Northern blot analysis on liver RNA derived from homozygous mice demonstrated that no detectable transcript is expressed from this allele. (J:80807)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Mocs1 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:80807
Lee HJ et al.,
"Molybdenum cofactor-deficient mice resemble the phenotype of human patients."
Hum Mol Genet 2002 Dec 15;11(26):3309-17
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All: |
3 reference(s)
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Analysis Tools
