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| Nomenclature |
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Symbol:
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Sgcatm1Eeng
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Name:
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sarcoglycan, alpha (dystrophin-associated glycoprotein);
targeted mutation 1, Eva Engvall
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MGI ID: |
MGI:2656910 |
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Synonyms: |
ASG - |
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Gene:
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Sgca
Location:
Chr11:94962791-94976327 bp, - strand
Genetic Position: Chr11,
59.01 cM, cytoband C
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:59165
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Parent Cell Line:
| Other (see notes) (ES Cell) |
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Strain of Origin:
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129S/SvEv
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Portions of exons 1 and 2 and all of intron 1 were replaced with a cassette containing lacZ and neo. The absence of normal protein in homozygous mutant mice was verified by immunofluorescence and Western blot analysis. (J:59165)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Sgca Mutation:
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9 strains or lines available |
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Notes |
ES cell line = SM38.
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| References |
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Original: |
J:59165
Liu LA et al.,
"Sarcoglycan isoforms in skeletal muscle."
J Biol Chem 1999 Dec 31;274(53):38171-6
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All: |
5 reference(s)
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Analysis Tools
