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| Nomenclature |
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Symbol:
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Atrtm2Bal
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Name:
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ataxia telangiectasia and Rad3 related;
targeted mutation 2, David Baltimore
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MGI ID: |
MGI:2656567 |
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Synonyms: |
ATRflox |
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Gene:
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Atr
Location:
Chr9:95857597-95951644 bp, + strand
Genetic Position: Chr9,
50.27 cM, cytoband E4
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:83042
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: LoxP sites were inserted flanking exons encoding essential regions of the kinase domain. An adjacent frt-flanked neomycin and thymidine kinase cassette was removed by Flp-mediated recombination in ES cells prior to the production of mice. (J:83042)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Atr Mutation:
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10 strains or lines available |
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| References |
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Original: |
J:83042
Brown EJ et al.,
"Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance."
Genes Dev 2003 Mar 1;17(5):615-28
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All: |
10 reference(s)
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Analysis Tools
