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| Nomenclature |
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Symbol:
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Tg(GFAP-cre)8Gtm
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Name:
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transgene insertion 8, David H Gutmann
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MGI ID: |
MGI:2656248 |
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Synonyms: |
GFAPCre, GFAP-Cre, GFAP-Cre-IRES-LacZ |
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Transgene:
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Tg(GFAP-cre)8Gtm
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6 x CBA
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: This transgene expresses Cre recombinase and beta-galactosidase under the control of the human glial fibrillary acidic (GFAP) promoter. This transgene is expressed in astrocytes by embryonic day 14.5. Two lines 1 and 8 were analyzed further for cre activity and expression. Both gave identical results, with data for line 8 presented in the reference.
(J:77208)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:77208
Bajenaru ML et al.,
"Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation."
Mol Cell Biol 2002 Jul;22(14):5100-13
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All: |
23 reference(s)
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Analysis Tools
