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| Nomenclature |
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Symbol:
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Cd40tm1Geha
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Name:
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CD40 antigen;
targeted mutation 1, Raif S Geha
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MGI ID: |
MGI:2655321 |
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Synonyms: |
CD40-, CD40M |
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Gene:
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Cd40
Location:
Chr2:165055627-165072948 bp, + strand
Genetic Position: Chr2,
85.38 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:82369
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The gene was disrupted by replacement of exons 7, 8, and 9 with a neomycin resistance cassette via homologous recombination. (J:82369)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cd40 Mutation:
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9 strains or lines available |
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| References |
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Original: |
J:82369
Castigli E et al.,
"CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation."
Proc Natl Acad Sci U S A 1994 Dec 6;91(25):12135-9
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All: |
18 reference(s)
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