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| Nomenclature |
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Symbol:
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Rag2tm1.1Cgn
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Name:
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recombination activating gene 2;
targeted mutation 1.1, University of Cologne
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MGI ID: |
MGI:2654909 |
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Synonyms: |
RAG-2del |
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Gene:
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Rag2
Location:
Chr2:101624718-101632529 bp, + strand
Genetic Position: Chr2,
53.87 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:72214
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Parent Cell Line:
| Bruce 4 (ES Cell) |
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Strain of Origin:
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B6.Cg-Thy1a
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: This allele is a derivative of Rag2tm1Cgn in which the sequences flanked by loxP sites were deleted in vivo by crossing mice carrying this allele to a deleter strain. (J:72214)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:72214
Hao Z et al.,
"Homeostasis of peripheral b cells in the absence of b cell influx from the bone marrow."
J Exp Med 2001 Oct 15;194(8):1151-64
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All: |
13 reference(s)
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