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| Nomenclature |
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Symbol:
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Ndntm1Alb
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Name:
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necdin;
targeted mutation 1, Arthur L Beaudet
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MGI ID: |
MGI:2653065 |
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Synonyms: |
deltaNdn, Ndn- |
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Gene:
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Ndn
Location:
Chr7:62348277-62349928 bp, + strand
Genetic Position: Chr7,
34.36 cM, cytoband C
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:55267
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Parent Cell Line:
| AB2.2 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprtb-m2
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: A cassette containing sequence encoding beta-galactosidase and neo was inserted at the endogenous locus via homologous recombination. Transcript was undetected by Northern blot analysis of brain and liver tissue obtained from heterozygous male and female mice carrying a paternal mutant allele. (J:55267)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ndn Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:55267
Tsai TF et al.,
"Necdin-deficient mice do not show lethality or the obesity and infertility of Prader-Willi syndrome [letter]"
Nat Genet 1999 May;22(1):15-6
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All: |
3 reference(s)
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Analysis Tools
