|
|
| Nomenclature |
|
Symbol:
|
Ndntm2Stw
|
|
Name:
|
necdin;
targeted mutation 2, Colin L Stewart
|
|
MGI ID: |
MGI:2653048 |
|
Synonyms: |
Ndn-null |
|
Gene:
|
Ndn
Location:
Chr7:62348277-62349928 bp, + strand
Genetic Position: Chr7,
34.36 cM, cytoband C
|
|
Mutation origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:57890
|
|
Parent Cell Line:
| W9.5/W95 (ES Cell) |
|
Strain of Origin:
|
129S1/Sv-Oca2+ Tyr+ Kitl+
|
|
Mutation description |
|
Allele
Type: | |
Targeted (Reporter) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: The floxed neo cassette was excised from Ndntm1Stw via in vivo cre mediated recombination. Sequence encoding lacZ was left in place of protein coding sequence downstream of the endogenous codon 31. (J:57890)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:57890
Gerard M et al.,
"Disruption of the mouse necdin gene results in early post-natal lethality [see comments]"
Nat Genet 1999 Oct;23(2):199-202
|
|
All: |
10 reference(s)
|
|