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| Nomenclature |
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Symbol:
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Ndntm1Stw
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Name:
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necdin;
targeted mutation 1, Colin L Stewart
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MGI ID: |
MGI:2653045 |
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Gene:
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Ndn
Location:
Chr7:62348277-62349928 bp, + strand
Genetic Position: Chr7,
34.36 cM, cytoband C
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:57890
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Parent Cell Line:
| W9.5/W95 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The majority of the protein coding region of endogenous allele was replaced with a cassette containing lacZ and floxed neo. 31 5' codons were left intact. The expression pattern of lacZ differed from the expression pattern observed for Ndntm2Stw, which lacked the floxed neo sequence. (J:57890)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:57890
Gerard M et al.,
"Disruption of the mouse necdin gene results in early post-natal lethality [see comments]"
Nat Genet 1999 Oct;23(2):199-202
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All: |
3 reference(s)
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Analysis Tools
