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| Nomenclature |
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Symbol:
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CryaaAey7
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Name:
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crystallin, alpha A;
dominant cataract 7
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MGI ID: |
MGI:2653028 |
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Synonyms: |
Aey7 |
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Gene:
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Cryaa
Location:
Chr17:31677945-31681724 bp, + strand
Genetic Position: Chr17,
17.09 cM, cytoband A3-B
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Mutation
origin |
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Strain of Origin:
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C3HeB/FeJ
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: The mutation is a T-to-A substitution at position 371 of the mRNA, which corresponds to a region in exon 3. This is predicted to cause a valine to glutamic acid replacement at codon 124. (J:72928)
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Inheritance: | |
Dominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cryaa Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:72928
Graw J et al.,
"Characterization of a new, dominant V124E mutation in the mouse alphaA-crystallin-encoding gene."
Invest Ophthalmol Vis Sci 2001 Nov;42(12):2909-15
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All: |
1 reference(s)
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Analysis Tools
