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| Nomenclature |
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Symbol:
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Plcb1tm1Hssh
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Name:
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phospholipase C, beta 1;
targeted mutation 1, Hee-Sup Shin
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MGI ID: |
MGI:2652485 |
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Synonyms: |
PLC-beta1-, PLCBeta1- |
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Gene:
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Plcb1
Location:
Chr2:134786159-135475258 bp, + strand
Genetic Position: Chr2,
65.66 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:43077
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: The exon encoding amino acids 50 through 82 was disrupted by a neomycin selection cassette inserted by homologous recombination. (J:43077)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Plcb1 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:43077
Kim D et al.,
"Phospholipase C isozymes selectively couple to specific neurotransmitter receptors."
Nature 1997 Sep 18;389(6648):290-3
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All: |
16 reference(s)
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