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| Nomenclature |
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Symbol:
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Plekha5Tg(AMH-cre)1Flor
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Name:
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pleckstrin homology domain containing, family A member 5;
transgene insertion 1, Florian Guillou
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MGI ID: |
MGI:2450300 |
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Synonyms: |
AMH-Cre, Mis-Cre |
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Gene:
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Plekha5
Location:
Chr6:140424099-140594906 bp, + strand
Genetic Position: Chr6,
70.34 cM
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x SJL)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: The transgene consists of a human AMH promoter, a cre recombinase gene, and genomic sequences from MT1 to provide mRNA secondary structure stability. The gene trap inserted into intron 3. Northern blot analysis shows gonad-specific transgene expression in Sertoli cells of 6 day old male mice and granulosa cells of 16 day old female mice. RT-PCR confirmed normal endogenous gene expression. (The insertion site of the original cre transgene was subsequenly identified as intron 3 of Plekha5.) (J:81650, J:189585)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:81650
Lecureuil C et al.,
"Sertoli and granulosa cell-specific Cre recombinase activity in transgenic mice."
Genesis 2002 Jul;33(3):114-8
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All: |
45 reference(s)
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Analysis Tools
