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| Nomenclature |
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Symbol:
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Rb1tm3Tyj
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Name:
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retinoblastoma 1;
targeted mutation 3, Tyler Jacks
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MGI ID: |
MGI:2450162 |
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Synonyms: |
Rb12lox, Rbf, RbloxP |
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Gene:
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Rb1
Location:
Chr14:73183673-73325822 bp, - strand
Genetic Position: Chr14,
38.73 cM, cytoband D3
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:81643
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Single loxP sites flank exon 3. (J:81643)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:81643
MacPherson D et al.,
"Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system."
Mol Cell Biol 2003 Feb;23(3):1044-53
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All: |
32 reference(s)
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