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| Nomenclature |
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Symbol:
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Ly6atm1Pmf
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Name:
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lymphocyte antigen 6 complex, locus A;
targeted mutation 1, Patrick M Flood
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MGI ID: |
MGI:2449938 |
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Synonyms: |
Ly-6A-, Sca-1- |
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Gene:
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Ly6a
Location:
Chr15:74994878-74997634 bp, - strand
Genetic Position: Chr15,
34.29 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:42594
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Parent Cell Line:
| E14TG2a (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The gene was disrupted by replacement of exons 1-3 with a neomycin resistance cassette via homologous recombination. Absence of gene expression was confirmed by flow cytometric analysis of splenocytes from homozygous mutant animals. (J:42594)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ly6a Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:42594
Stanford WL et al.,
"Altered proliferative response by T lymphocytes of Ly-6A (Sca-1) null mice."
J Exp Med 1997 Aug 29;186(5):705-17
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All: |
13 reference(s)
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Analysis Tools
