|
|
| Nomenclature |
|
Symbol:
|
Rag1tm1Bal
|
|
Name:
|
recombination activating gene 1;
targeted mutation 1, David Baltimore
|
|
MGI ID: |
MGI:2448994 |
|
Synonyms: |
Rag-1- |
|
Gene:
|
Rag1
Location:
Chr2:101638282-101649501 bp, - strand
Genetic Position: Chr2,
53.88 cM
|
|
Premature death and kidney disease in C1galt1ptl1/C1galt1ptl1 and C1galt1ptl1/C1galt1ptl1 Rag1tm1Bal/Rag1tm1Bal mice
Show the 1 image(s) involving this allele.
|
 |
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:18049
|
|
Parent Cell Line:
| J1 (ES Cell) |
|
Strain of Origin:
|
129S4/SvJae
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The gene was disrupted by insertion of a PGK-neo cassette into the coding region at amino acid 330 resulting in a frameshift mutation. (J:18049, J:92470)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:18049
Spanopoulou E et al.,
"Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice."
Genes Dev 1994 May 1;8(9):1030-42
|
|
All: |
62 reference(s)
|
|
Analysis Tools
