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| Nomenclature |
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Symbol:
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Tg(SMN2)89Ahmb
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Name:
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transgene insertion 89, Arthur H M Burghes
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MGI ID: |
MGI:2448989 |
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Synonyms: |
SMN2 |
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Transgene:
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Tg(SMN2)89Ahmb
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A 35.5 kb genomic fragment containing the human survival motor neuron 2 (SMN2) gene and promoter was used for the transgene. The transgene is ubiquitously expressed in all tissues examined by Northern blot analysis. Line 89 carries 1 copy of the transgene.
(J:60592)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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Mouse strains and cell lines available from the
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(IMSR)
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| References |
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Original: |
J:60592
Monani UR et al.,
"The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy."
Hum Mol Genet 2000 Feb 12;9(3):333-9
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All: |
55 reference(s)
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Analysis Tools
